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To cause permanent loss of function of a limb or part of the body
maim disable cripple incapacitate mutilate hurt impair injure wound lame hamstring disfigure mangle mar batter blemish break castrate crush damage deface deform dismember disqualify gimp hack harm hog-tie lacerate massacre maul mayhem spoil put out of action ruin cut wreck distort flaw scratch vitiate bruise scar total weaken tear slash endamage graze rend tear apart butcher cross up scrape tarnish debilitate compromise contort crab mangulate undermine gash vandalize twist slice immobilize blight smash stab defile abuse prostrate torture paralyze paralyse handicap bloody vandalise disfeature shatter rip slit immobilise mess up hit score warp split scathe puncture destroy nick carve taint stain disarm hack up beat unstrengthen blunt attenuate sap hock blot maltreat sabotage take out rough up foul up work over punish whip incise gouge molest traumatize amputate cleave buckle clip squinch trash cut open screw uglify malform dislimb misshape cut up gnarl torment torpefy mark traumatise lance pound wrench pierce ravage wing disenable knot skew plug enfeeble bend make unattractive pummel lash wince tear limb from limb inactivate ding contuse burn sully belt pinch make ugly flog knock punch unfit exhaust kibosh unbrace muzzle pinion hogtie enervate shake up smite whack pummelled bang up pollute pommel knock out throw monkey wrench in brutalize shoot down render incapable brutalise louse up brand notch annoy bow snick abrade shear despoil hobble touch poison darken affect make a mess of be a blot on the landscape make misshapen distort the shape of hinder upset disfashion shred furrow nip adulterate expurgate censor bowdlerize bend out of shape halt bowdlerise stop jam queer detract tweak put a damper on detract from deactivate freeze knife claw clip wings lay up clamp wheel-clamp blast irritate zap cut to pieces hash up savage jag tie prevent from moving bring to a standstill render inoperative make inoperative prevent from working action render inactive bring to a halt arrest invalidate indispose cut to ribbons ouch stick put out of commission devastate serrate persecute scourge knacker crool make powerless restrict make unfit spike render powerless open up undo desecrate gut demolish mistreat ill-treat pique aggrieve foul prejudice grieve pain wax distress sting annihilate disrupt disjoint dissect sever raze smirch grimace crack bleach play merry hell with do damage to infect wear away cause injury rot contaminate disintegrate dent scorch fade dirty dismantle drive a nail into the coffin of corrupt corrode wreak havoc on discolour smash up gnaw wrong play havoc with rust discolor tamper with afflict crucify martyr chop crumple do in draw blood do mischief to anatomize joint disarticulate slay cut about hash separate mash flay pulverize give someone the works inflict suffering on martyrize impale grill inflict pain on put on the rack sunder limb chop up put out cause pain to cause injury to pulverise sideline palsy stifle dislocate part slap spank slug flail cut off the limbs of make lame thrash buffet bash strike wallop assault belabour deck clobber lick thump pelt bang attack smack drub clout bat baste whop cudgel do club lace lambast lather whup curry beat up tonk hide tromp bludgeon bop hammer slog switch thwack whap slate lambaste birch belabor biff whale tan paddle thresh sock fib rain blows on knock about beat the living daylights out of lace into punch out lay one on knock around lay into do over dash against aim blows at knock into the middle of next week bung up give someone a good hiding tire drain weary fatigue wear out devitalize reduce soften poop overtire diminish etiolate frazzle waste lessen tire out lay low deplete wash out wear down fag out overtax decrease numb jade make feeble make weak tucker take it out of burn out conk out poop out peter out deaden benumb subvert tax bush drop wear dull tucker out wear to a frazzle obtund impoverish deteriorate lower depress scupper torpedo emasculate dilute impede unnerve threaten overextend overdo run ragged overexert draw overfatigue overwork bankrupt temper calm debase devaluate extenuate thin abate flag eviscerate assuage sink droop render infirm outwear bust harass kill soothe bedraggle languish sag fizzle succumb wipe out make weary water down take it out of one take the edge off do up put the kibosh on unhinge erode hospitalize encumber hamper suck dry use up sap your strength bring to a grinding halt unplug idle seize disempower make sleepy shake destabilize worsen invalid hospitalise exenterate disembowel shag out take wear on drain of energy lay someone up confine to a wheelchair confine to bed jeopardize have a bad effect on eat away rob from pull the rug out from under root turn off render inoperable wear oneself to a frazzle make tired nearly kill wear oneself to a shadow run into the ground dampen devalue cheapen put on the sick list shock inconvenience wither interfere with jeopardise screw up destabilise muck up seize up lose strength make useless become unable to move become immobilized grind to a halt become stuck cool be detrimental to cause detriment to do harm to allay moderate muffle throw a monkey wrench into mollify sate appease relieve slake damp alleviate cauterize ease contract tone down hebetate desensitise cauterise desensitize appall transfix bemuse daze close stun anesthetize petrify astound anaesthetize stupefy daunt nonplus appal constrict shrink deflate mitigate rarefy lighten dissipate offset fell floor overturn dash bore level burst explode nix pop scotch banjax blow down stop dead make inert shut down make nerveless bring to grinding halt dish wreak havoc with rattle blow up do for overthrow mow defeat knock down knock over put paid to blow a hole in bring to naught bring to nought mow down bowl over bowl down make helpless make impotent bring someone to their knees bring low

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