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pest nuisance bother annoyance pain hassle irritant vexation headache inconvenience aggravation trial peeve bugbear trouble exasperation irritation problem botheration irk nudnik drag ruffle frustration thorn bore rub aggro worry tease nudnick bane teaser nark gadfly scourge menace annoyer skelf curse nyaff persecutor blight blister gall gnawer pill pesterer nag blighter tormentor creep besetment nudge cuss pain in the bum pain in the neck hair shirt pain in the backside pain in the rear thorn in the flesh crashing bore thorn in one's side plague difficulty burden tribulation fair cow bind source of irritation torment source of annoyance distress affliction grief misfortune cross to bear provocation evil strain worriment misery cancer thorn in your side palaver rigmarole woe infliction suffering bummer canker pestilence pet peeve source of vexation hang-up corruption concern uphill upset disease calamity burr under someone's saddle stress torture ordeal hardship discomfort nemesis bane of one's life bitter pill burr in someone's saddle rot embarrassment disappointment gripe pinprick letdown sickness goad ruin hindrance visitation disaster nightmare poison adversity terror source of aggravation snag troublemaker downfall source of difficulty discouragement undoing infuriation pip drip grievance downer bête noire sore point comedown irksomeness sorrow travail bad experience bug issue rodent bringdown displeasure source of trouble struggle agitation fuss chagrin quagmire dilemma predicament care cross stressor pain in the behind mischief-maker schmo aggravator teasing unhappiness botherment bum pester louse offense offence obstacle frump insect cause for concern aversion trials and tribulations cause of annoyance waterloo anxiety dislike fizzle hate ghost poor excuse pressure disruption punishment penalty test handful molestation perplexity job inopportuneness flurry bellyache chip on your shoulder bad news cause of distress persecution snooze yawn tall order hard work snoozer anguish hurt excruciation harassment rack agony straits old one-two destruction dullsville thorny problem contamination pet hate soreness Waterloo bete noire yawner pollution droner nagging source of disruption uphill battle malignancy corrosion despair irritator stirrer motivator excitant stimulator mover meddler prod spur busybody energizer a thorn in someone's side ruination depression death mildew contagion fungus smutch infestation wretchedness trauma tragedy eyesore sight withering dump boring situation tedious thing tedious person tiresome thing bad situation tiresome person heartache fiasco bête noir heartbreak blow catastrophe misadventure debacle albatross drama down failure sadness dud fatal attraction blot on the landscape sad event ill fortune stroke of bad luck labour labor complication perturbation anger grind quandary drudgery load drawback pickle disquiet hitch exertion bedevilment disturbance setback indignation plight toil ire effort obstruction weight mess encumbrance chore imposition pitfall difficult task pestering tension drain harrying importunity bugging resentment pains umbrage disgruntlement pique bothering hurdle catch discontent killer beast millstone shock alarm confusion bear dread impediment strife discomposure barrier tough grind tough assignment hiccup stumbling block intrusion spanner in the works monkey wrench in the works no picnic battle animosity wrath antipathy enmity interruption demands badgering slog crunch problems heat unpleasantness awkwardness challenge disadvantage catch-22 provoking irking nervousness derangement choler urgency bustle vexing affront fear intimidation dispute crossness glitch hazard trepidation ado jam task uphill struggle scrape pressurization exigency pressurisation disquietude hot water unease dislocation dissatisfaction point at issue can of worms disputed point needling fright turmoil handicap dismay surprise trammel muddle nervous tension imbroglio mortification puzzle to-do being rubbed up the wrong way fly in the ointment exacerbation antagonization complaint objection case quibble conflict taunting demand irascibility disbenefit matter knot issues nettling plaguing workout scutwork anathema endeavor stirring interference ruffling charge onus injury insult pet aversion distraction whisking roiling convulsion duress facer pinch prob cumber row niggling insults indignity encroachment lack of comfort burdens exertions strenuousness laboriousness arduousness struggling brickbat mix-up hot potato tight spot vexed question question mark gremlin hornets' nest difficult situation obtrusion constraint restraint imposure painfulness hangup travails dolour consternation irritability long haul endeavour temper spleen fury rage bafflement dullard pressure of work panic horror fluster petulance tetchiness peevishness testiness snore snoozefest yawnfest snorefest hot temper bad temper apprehension disillusionment performance defeat shake-up disarray ill humour stroppiness discomfiture weariness crabbiness churning up stirring up mental burden waste of time boring event boring thing boring person mind-numbing experience nonevent uneasiness disenchantment reversion commotion queasiness hard time backbreaker dumps the blahs blue funk blues funk cold feet tizzy turn-up subversion hard row to hoe hard mountain to climb pressure cooker outrage work gruntwork slavery donkeywork tenseness heavy labor hard graft donkey-work heavy labour difficult project donkey work hard labour backbreaking work delay check hold-up coercion disapproval stoppage fix entanglement block opposition thought question oppression restlessness ferment hole joker gotcha gimmick corner habit count squeeze downside doubt disagreement complexity ill feelings bad feelings mishap overextension misgiving distention intensity mistrust passion flutter apprehensiveness fearfulness expenditure negative aspect controversy booby trap holdup land mine snafu tangle discontinuance brouhaha enmeshment embroilment hard feelings wounded feelings expectancy impatience rigor sweat attention box teething trouble tight corner rigour while sticky situation deep water soap opera complicated situation elbow grease

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